Since 2018 there are multitudes of studies around the CBD cannabinoid (as well as many other cannabinoids) providing insight into the efficacy of CBD on the human body. Cannabidiol (CBD) is one of 100 cannabinoids found in the hemp plant. There are a number of these cannabinoids, including CBD which are used for various physical and mental challenges our customers face each day.
The human body has The endocannabinoid system (ECS) which is a biological system composed of endocannabinoids. These are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors (CBRs), and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system (including the brain) and peripheral nervous system.
There are two main types of CB receptors throughout the human body which vary in their chemical structure and thus perform different functions in terms of diet, lifestyle, and nutrition
Experts are still trying to fully understand the ECS. But so far, we know it plays an important role in regulating a range of functions and processes, including:
- reproduction and fertility
The ECS exists and is active in your body even if you don’t use hemp.
Cannabinoid Receptor 1 (CB1) is associated with psychoactive, neuromodulatory, and analgesic effects due to its activation by a lipid called tetrahydrocannabinol (THC). CB1 is mostly expressed in the brain, adipocytes (fat cells), hepatocytes (liver cells), and musculoskeletal tissues.
Cannabinoid Receptor 2 (CB2) is associated with anti-inflammatory and immunomodulatory effects but no psychoactive effects. CB2 is expressed in body cells controlling immune function and (potentially) the central nervous system (CNS). Additionally, research suggests that secondary metabolites from phytonutrients in plant-based foods (such as CBD products) enhance the activity of CB2 receptors and confer healthy inflammatory responses.
Essentially our bodies are predisposed to gain benefits from hemp cannabinoids as they bind to these receptors in our respective bodies.
Possible Side Effects of CBD
CBD is generally considered safe for users. However, users may experience mild side effects such as:
- Changes in appetite
- Changes in weight
CBD may also interact with certain prescription medications, dietary supplements, and over-the-counter drugs.
More commonly, it is known to interact with medications that contain a grapefruit warning. Nevertheless, it is essential to speak with your physician to discuss potential side effects before using CBD products.
Since CBD is now legal in every state in the United States, many people are interested in using CBD products. The FDA has recognized the potential for CBD to help treat numerous ailments and has ramped up studies to fill in current gaps in scientific evidence.
Although we need extensive studies to verify its effectiveness and side effects, research appears very promising. CBD seems to be a natural complement to the traditional treatment of a wide variety of health conditions. However, if you’re considering using CBD, it’s essential to speak with your healthcare provider to discuss potential risks and benefits before use.